Uptown Blues - Key of C. We still have that shuffle, but this time with a cool jazzy feel to it. This kind of sound comes from Chicago and was popularised by among others, Memphis Minnie. The lead guitar in the sample is playing blues, but with a tinge of jazz in its expression. The slide guitar is played in the style of Casey Bill Weldon in open G tuning (DGDGBD). Try copying the piano licks on your guitar. Chuck Berry was influenced by this kind of sound and many of his signature licks work well on this one.